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302 results found in Imaging Mass Cytometry

  • consumable

    Anti-Human Smooth Muscle Actin (1A4)-141Pr—25 µg

    Alpha smooth muscle actin is a 42 kDa cytoskeletal protein expressed in smooth muscle cells of blood vessels, myofibroblasts and myoepithelial cells. …

    Product #: 3141017D

  • consumable

    Anti-Human p53 (DO-7)-143Nd—25 µg

    p53 is a 53 kDa protein that operates as a tumor suppressor and helps regulate hundreds of genes in response to various types of stress. …

    Product #: 3143026D

  • consumable

    Anti-Human T-bet/TBX21 (D6N8B)-145Nd—25 µg

    T-bet (Tbx21) is a transcription factor bearing a T-box DNA-binding domain. It is considered a master-regulator of the Th1 CD4+ T cell subset. …

    Product #: 3145015D

  • consumable

    Anti-Human Syk (4D10.2)-149Sm—25 µg

    Syk is a cytoplasmic 72 kDa nonreceptor tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells. …

    Product #: 3149024D

  • consumable

    Anti-Human CD15 (W6D3)-149Sm—25 µg

    CD15, also known as LewisX, 3-FAL and SSEA-1, is a carbohydrate adhesion molecule, 3-fucosyl-N-acetyllactosamine (3-FAL). …

    Product #: 3149026D

  • consumable

    Anti-Human PD-L1 (E1L3N)-150Nd—25 µg

    PD-L1, also known as CD274, is one of the ligands for programmed death 1 (PD-1), and is an immune-inhibitory receptor belonging to the CD28/cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) family. …

    Product #: 3150031D

  • consumable

    Anti-Human CD45 (D9M8I)-152Sm—25 µg

    CD45, also known as leukocyte common antigen (LCA) and T200, is expressed on the plasma membrane of all hematopoietic cells except mature red blood cells and platelets. …

    Product #: 3152018D

  • consumable

    Anti-Human IDO (D5J4E)-155Gd—25 µg

    Indoleamine-2,3-dioxygenase (IDO) is an intracellular enzyme that catalayzes the degradation of tryptophan to kynurenines. IDO is considered to be an immunosuppressive molecule that limits T cell proliferation and activation through trytophan starvation of T cells. …

    Product #: 3155017D

  • consumable

    Anti-Human CD68 (KP1)-159Tb—25 µg

    CD68, also known as macrosialin, is predominantly an intracellular protein found in the late endosomal compartment but can also be detected in small amounts on the surface of myeloid-derived cells. …

    Product #: 3159035D

  • consumable

    Anti-Human CD20 (H1)-161Dy—25 µg

    CD20, also known as B1 and Bp35, is a transmembrane spanning protein expressed on pre-B cells, immature and mature B cells, and some follicular dendritic cells. …

    Product #: 3161029D

  • consumable

    Anti-Human Pan-Keratin (C11)-162Dy—25 µg

    Keratins (cytokeratins) are a group of intermediate filament proteins that are mainly expressed in epithelial cells. …

    Product #: 3162033D

  • consumable

    Anti-Human CD8a (D8A8Y)-162Dy—25 µg

    CD8 is found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells. CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition. …

    Product #: 3162035D

  • consumable

    Anti-Human c-Myc p67 (9E10)-164Dy—25 µg

    c-myc protein is a transcription factor and proto-oncogene that binds to DNA and activates transcription as part of a heterodimeric complex with Max. …

    Product #: 3164025D

  • consumable

    Anti-Human CD223/LAG-3 (D2G40)-153Eu—25 µg

    Lymphocyte activation gene 3 (LAG-3), also known as CD223, shares homology with CD4, and LAG-3 binding to MHC class II is thought to contribute to the negative regulation of T cell activation. …

    Product #: 3153028D

  • consumable

    Anti-Human FoxP3 (236A/E7)-155Gd—25 µg

    Foxp3, a member of the Fox protein family of transcriptional regulators, is a master regulator of the regulatory T (Treg) CD4+ T cell subset. …

    Product #: 3155016D

  • consumable

    Anti-Human Vista (D1L2G)-160Gd—25 µg

    VISTA, also known as B7-H5, is a 55–65 kDa transmembrane protein belonging to the Ig superfamily primarily expressed by myeloid cells. It is a negative checkpoint control protein that regulates T cell activation and immune responses. …

    Product #: 3160025D

  • consumable

    Anti-Human pNFkBp65 [S529] (K10x)-166Er—25 µg

    NFκB-p65, also known as RelA, is a subunit of the NFκB transcription factor complex, an important mediator of inflammatory and immune responses. …

    Product #: 3166026D

  • consumable

    Anti-Human Pan-Keratin (C11)-148Nd—25 µg

    Keratins (cytokeratins) are a group of intermediate filament proteins that are mainly expressed in epithelial cells. …

    Product #: 3148020D

  • consumable

    Anti-Human CD45RA (HI100)-166Er—25 µg

    CD45RA is a specific splice variant of the transmembrane tyrosine phosphatase CD45. The CD45RA isoform is most highly expressed on resting/naive T cells, B cells, and monocytes. …

    Product #: 3166028D

  • consumable

    Anti-Human Met (D1C2)-167Er—25 µg

    The c-Met receptor, also called hepatocyte growth factor receptor (HGFR) is a member of the receptor tyrosine kinase family that induces cell proliferation, survival, motility and invasion. …

    Product #: 3167020D