Consumables

Anti-Mouse FceR1a (MAR-1)-176Yb—100 Tests

FcεRI is a member of the multichain immune recognition receptor family and exists as a tetrameric complex (αβγ2). The α chain, a member of the immunoglobulin superfamily, contains the binding site for IgE but lacks intrinsic signaling ability, which is carried out by the β and γ subunits. FcεRIα is expressed on mast cells and basophils and up-regulated by the presence of IgE. The FcεRI complex plays an important role in triggering IgE-mediated allergic responses by causing the release of chemical mediators such as histamine. The MAR-1 monoclonal antibody reacts with the α subunit of the FcεRI complex.

• Species:
  Mouse
• Clone:
  MAR1
• Target:
  FceR1a
• Tag:
  176Yb
• Quantity:
  100 Tests