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Consumables

Anti-Human CD8a (D8A8Y)-162Dy—25 µg

CD8, also known as T8 and Leu2, is a type I membrane glycoprotein consisting of two disulfide-linked chains (CD8a, CD8b). CD8 is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I, and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

  • Species:
    Human
  • Clone:
    D8A8Y
  • Target:
    CD8a
  • Tag:
    162Dy

 

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