CD27, also known as S152 and T14, is a type 1 membrane protein. It binds to CD70 and plays a key role in regulating B cell activation and immunoglobulin synthesis. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation. It is expressed on a subset of thymocytes, NK cells, some B cells, and virtually all mature T cells. It is up-regulated upon T cell activation.
Anti-Human CD27 (L128)-155Gd—100 Tests
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Species:Human
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Clone:L128
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Target:CD27
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Tag:155Gd
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Quantity:100 Tests
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