Consumables

Anti-Human CD182/CXCR2 (5E8/CXCR2)-147Sm—100 Tests

CD182, also known as CXCR2 or IL-8 receptor B (IL-8RB), is a 67–70 kDa member of the 7-transmembrane-spanning G protein-coupled receptor (GPCR) family. CD182 is expressed as a homodimer, or a heterodimer with CD181 (CXCR1, IL-8RA), and is expressed on granulocytes, NK cells, a subset of T cells, mast cells, monocytes, endothelial cells, megakaryocytes, and oligodendrocytes. CD182 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis upon binding its ligands including IL-8 (CXCL8), NAP-2 (CXCL7), GCP-2 (CXCL6), and GRO-α,β,γ (CXCL1, CXCL2, CXCL3).

• Species:
  Human
• Clone:
  5E8/CXCR2
• Target:
  CD182
• Tag:
  147Sm
• Quantity:
  100 Tests