An essential mechanism of cellular signal transduction is the phosphorylation of proteins at tyrosine, threonine, and serine residues. An increase in total cellular phosphotyrosine levels indicates a shift in the balance of tyrosine protein kinases and phosphases. Constitutively high total phosphotyrosine levels can be indicative of a dysregulated kinase, as in the case of the oncogenic BCR-ABL fusion protein.
Anti-pTyrosine (Tyr100)-144Nd—50 Tests
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Species:Cross
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Clone:Tyr100
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Target:pTyrosine
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Tag:144Nd
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Quantity:50 Tests
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