Consumables

Anti-EGFR (D38B1)-142Nd—25 µg

Epidermal growth factor receptor (EGFR), also known as ErbB-1 and HER1 in humans, is a transmembrane glycoprotein that is a member of the protein kinase superfamily for cell growth and differentiation regulation. EGFR binds to epidermal growth factor and transforming growth factor α (TGFα). Ligand binding induces receptor dimerization and tyrosine autophosphorylation, initiating the MAPK, Akt and JNK signal transduction pathways towards DNA synthesis and cell proliferation. EGFR is expressed or highly expressed in a variety of human tumors of epithelial origin.

• Species:
  Cross, Human
• Clone:
  D38B1
• Target:
  EGFR
• Tag:
  142Nd
• Quantity:
  25µg
• Sample Type:
  FFPE