Discover Your Inner Cell
Whether investigating therapeutic response in a human subject or a mouse model of disease, getting the most information from every precious sample is a priority in clinical and research studies alike.
Mass cytometry with Helios™ uses CyTOF® technology to enable deep profiling of translational and clinical research samples across a range of cell surface and intracellular markers.
Designed to significantly reduce signal overlap, mass cytometry empowers researchers to simultaneously interrogate cellular phenotypes, function and signaling status in higher dimension than traditional fluorescence methods.
ComprehensiveAccelerate insight into mechanisms of health and disease with the most comprehensive view of cell phenotype and function. |
PowerfulObtain the most actionable information from precious samples. |
ProvenTrusted by translational and clinical study researchers around the world to power life changing insights in human health. |
Hear what researchers are saying about the power of mass cytometry
テクノロジー
Mass cytometry uniquely combines time-of-flight mass spectrometry with Maxpar metal-labeling technology to enable breakthrough discovery and comprehensive functional profiling applications. Cellular targets are labeled with metal-tagged antibodies and detected and quantified by time-of-flight mass spectrometry. The high purity and choice of metal isotopes provide minimal background noise from signal overlap or endogenous cellular components. And 135 available detection channels ensure an ongoing ability to add more parameters, enabling you to fully study the functional complexity of biological systems at the single-cell level.
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構成
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仕様
Helios System
Channels | 135 |
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Mass range | 75–209 amu |
Abundance sensitivity | 0.3% for 159Tb |
Instrument response | 600,000 counts/pg 159Tb |
Detection limit | 350 antibodies/cell |
Dynamic range | 4.5 orders of magnitude |
Calibration | Automated |
Operating system | Windows® 7 Pro 64-bit |
Data storage | 7.2TB HDD RAID (mirrored) |
Sample introduction | Pneumatic single tube loader with agitation, up to 5 ml volume |
Peak throughput | 2,000 (events/sec) |
Flow rate | 30–45 (µL/min)
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Replicate sample CV (normalized) | <3% |
Height | 52 in (132 cm) |
Width | 41 in (103 cm) |
Depth | 35 in (87 cm) |
Weight | 705 lb (320 kg) |
Chiller
Height | 25 in (64 cm) |
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Width | 15 in (38 cm) |
Depth | 27 in (69 cm) |
Weight | 178 lb (81 kg) |
Workstation
Operating system | Windows 7 Pro 64-bit |
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CPU | Intel® Core™ i7 |
Hard drives | 2 x SSD, RAID 1 |
Data storage | 7.2TB HDD, RAID 10 |
Monitor | 24 in (61 cm) LED |
Height | 18 in (46 cm) |
Width | 8 in (20 cm) |
Depth | 23 in (58 cm) |
Weight | 77 lb (35 kg) |
Data File Size
IMD | 0.3 MB/sec/channel |
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FCS | 12.4 bytes/event/channel |
TXT | 2.4 bytes/event/channel |